Obese Adolescents With PCOS Have Altered Biodiversity and Relative Abundance in Gastrointestinal Microbiota
نویسندگان
چکیده
منابع مشابه
Endometria from Obese PCOS Women with Hyperinsulinemia Exhibit Altered Adiponectin Signaling.
Hyperandrogenemia, hyperinsulinemia, and obesity affect 60-70% of patients with Polycystic Ovarian Syndrome (PCOS), who exhibit an altered endometrial insulin signaling. The aim of the study was to evaluate whether hyperandrogenism, hyperinsulinism, and obesity present in PCOS patients impair the endometrial adiponectin signaling pathway. The ex vivo study was conducted on 27 samples from lean ...
متن کاملAssociation between adiponectin with insulin and blood sugar levels in obese adolescents in comparison with normal weight adolescents
Introduction: The growing number of obesity and excess of body fat mass in adolescents in recent years and also increasing prevalence of chronic diseases associated with obesity in Iranian adolescents, tends to develop this study. The present was aimed to investigate relationship between adiponectin level with some of biochemical and anthropometric index in obese and normal weight adolesc...
متن کاملDysbiosis of Gut Microbiota Associated with Clinical Parameters in Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder in women. Gut microbiota has been implicated to play a critical role in metabolic diseases and may modulate the secretion of mediators of the brain-gut axis. Interaction between gut microbiota and the endocrine and biochemical disturbances in PCOS still remains elusive. Here, we showed an altered gut microbiota signif...
متن کاملMetformin treatment is effective in obese teenage girls with PCOS.
BACKGROUND Polycystic ovary syndrome (PCOS) is the most frequent cause of menstrual disorders in teenage girls. Little information is available about the effects of metformin in adolescent girls with PCOS and its dose and its efficacy in regulating menstrual cyclicity and hyperandrogenic symptoms. We evaluated the effects of metformin treatment on ovulatory function, hirsutism, acne, hormonal p...
متن کامل[Microbiota and gastrointestinal diseases].
The bacterial colonisation is established immediately after birth, through direct contact with maternal microbiota, and may be influenced during lactation. There is emerging evidence indicating that quantitative and qualitative changes on gut microbiota contribute to alterations in the mucosal activation of the immune system, leading to intra- or extra-intestinal diseases. A balance between pat...
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ژورنال
عنوان ژورنال: The Journal of Clinical Endocrinology & Metabolism
سال: 2020
ISSN: 0021-972X,1945-7197
DOI: 10.1210/clinem/dgz263